Epitalon
Epithalon / Epithalamin
Telomerase activator — longevity peptide
About
A Russian peptide that activates the telomerase enzyme and lengthens telomeres. The most-studied longevity peptide.
Mechanism
Increases telomerase activity, preserving telomere length. Also promotes melatonin production.
Dosage
Draw to 50 units on a U-100 insulin syringe
10 mg · 1 mL BAC
When to take: In the evening before sleep (improves melatonin).
Reconstitution
Vial size (mg): 10 mg · BAC water (mL): 1 mL · Concentration: 10 mg/mL
Use within 30 days after reconstitution.
Dosing reference
Units to draw at the typical dose range, per vial size.
| Vial | Water | Typical draw |
|---|---|---|
| 10 mg | 1 mL | 50–100 units |
| 50 mg | 1 mL | 10–20 units |
Benefits
- Telomerase activation
- Improved sleep
- Improved melatonin production
- Antioxidant
- Possible longevity effects (animal data)
- Skin health
Side effects
- Very well tolerated
- No significant side effects reported in trials
Gender notes
Cautions
- Pregnancy
- Active cancer (telomerase activation could theoretically stimulate it)
Research
- Khavinson V: Peptides and aging
Neuroendocrinology Letters · 2002
20+ years of research on epitalon and longevity in Russia.
- Khavinson V et al: Epitalon and telomere length
Bulletin of Experimental Biology and Medicine · 2003
Epitalon increases telomerase activity and lengthens telomeres in vitro.